Monthly Archives: January 2013

How does the ER ensure proteins are correctly folded?

What is the ER Quality Control Mechanism? Chaperone proteins are involved in assisting protein translocation, retaining unfolded proteins in the ER, and mediating the unfolded protein response. There are 3 main ER Chaperone proteins involved:         I.            BIP Binds to exposed amino acid sequences that are normally buried in the interior of a […]

P Elements of Drosophila Melanogaster

What are P Elements? P elements are DNA transposable elements, that carry genes required for transposase activity and genes that encode a repressor that prevents expression of transposase. P elements have a characteristic 31bp inverted repeat at both ends of the element. P elements can be either full length or short length. The full length […]

Noncoding DNA and Genome Evolution

Noncoding DNA and Genome Evolution   Noncoding DNA, why does it exist? There are many possibilities but it is thought that noncoding DNA has a function that has not yet been discovered hence why the cell is maintain it – it is essential for proper cell function. Another possibility is that noncoding sequences might be […]

Genome Evolution

There are two fundamentally different ways in which new genes could be acquired by a genome: By duplicating some or all of the existing genes in the genome. By acquiring genes from other species. Gene Duplication Mechanisms of Duplication There are many ways by which short segments of DNA containing one or a few genes […]